I don't think Hutchinson is calling the part of Main Street south of Sherman "Old Town" officially but that is really what it is.
This plaque is on the southwest corner of Avenue B and Main.
The present occupant is Apron Strings, a kitchen supply store and site of many cooking lessons and demos.
This was the location of Weeks Drug in the 1960's and I don't remember any of the other establishments.
The idea of identifying what business was there before is a neat idea for the history lovers.